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Mouse DKK1-His Antibody Both proteins contain a NAD+

SKU: 20637470946

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Description

Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases

28 (3): 605-7

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Mouse DKK1-His Antibody Both proteins contain a NAD+The dickkopf family of proteins are secreted proteins characterized by two cysteine rich domains that mediate protein protein interactions. The encoded protein binds to the LRP6 co receptor and inhibits beta catenin dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote

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