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(S)-Lisofylline Catalog No.:M22422-C showing a greater affinity at

SKU: 61704521958

4.4
USD100.00 USD142.00

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Description

showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials

InChi: InChI=1S/C10H8N4O3S

which is similar to penicillin

which inhibits rat liver microsomal squalene synthase with an IC50 of 0

Solubility: DMSO : ≥ 100 mg/mL (301

(S)-Lisofylline Catalog No.:M22422-C showing a greater affinity atLisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,

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