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24(4):873-6
Smiles: CC(C)(O)C(=O)N1CCN(CC1)C1=CC(C2=C(C3=CNC4=CC=CC=C43)C(=O)NC2=O)=C(C=C1)C(F)(F)F
Solubility: DMSO up to 20 mM
and inhibited proteasome function in skin and muscle
Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide production
XE991 2HCl 444217 24(4):873-6XE991 2HCl is a potent and selective blocker of KV7 (KCNQ) voltage gated potassium channels which blocks KV7. 2+7. 3 (KCNQ2+3) M currents (IC50 = 0. 6 0. 98 M) and KV7. 1 (KCNQ1) homomeric channels (IC50 = 0. 75 M) but is less potent against KV7. 1 minK channels (IC50 = 11. 1 M). Product information CAS Number: 122955 13 9 Molecular Weight: 449. 37 Formula: C26H22Cl2N2O Chemical Name: 10,10 bis(4 pyridinylmethyl) 9(10H) anthracenone, dihydrochloride