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Abaloparatide TFA o-PEG3-alcohol InChiKey: OJFKUJDRGJSAQB-UHFFFAOYSA-N

SKU: 22145261399

4.3
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Description

InChiKey: OJFKUJDRGJSAQB-UHFFFAOYSA-N

Manning Fox JE

InChi: InChI=1S/C26H24Cl3NO/c1-2-3-10-30-15-25(31)24-14-19(29)13-23-21(11-16-4-6-17(27)7-5-16)22-12-18(28)8-9-20(22)26(23)24/h4-9

TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

InChi: InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26

Abaloparatide TFA o-PEG3-alcohol InChiKey: OJFKUJDRGJSAQB-UHFFFAOYSA-NAbaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue selected to be a potent and selective activator of the PTHR1 signaling pathway. Abaloparatide TFA enhances Gs cAMP signaling (EC50 of 0. 3 nM) and arrestin recruitment (EC50 of 0. 9 nM) in MC3T3 E1 osteoblast cells. Product information Chemical Name: Ala Val Ser Glu His Gln Leu Leu His Asp Lys Gly Lys Ser Ile Gln Asp Leu Arg Arg Arg Glu Leu Leu Glu Lys Leu Leu {Aib}

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