Pay in 4 interest-free payments of $26.77 Learn more
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
InChiKey: WSMXAUJFLWRPNT-DIVCQZSQSA-N
CAS Number: 71617-10-2
Apilimod mesylate
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma
Formula: C23H18ClF2N3O3S
K-7174 dihydrochloride iophen-2-yl)-2-(2-(m-tolyl)hydrazono)butane-1 3-dione InChiKey: WSMXAUJFLWRPNT-DIVCQZSQSA-NK 7174 is a novel orally active, potent proteasome inhibitor. K 7174 exerts anti myeloma activity in vitro and in vivo by down regulating the expression of class I histone deacetylases. K 7174 kills bortezomib resistant myeloma cells carrying a 5 subunit mutation in vivo and primary cells from a patient resistant to bortezomib. K 7174 is also a GATA specific inhibitor, which may have potential application in treating anemia of chronic disease. Product