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the receptor complex is internalized via the cellular endosomal machinery
Smiles: CN1CCN(CC1)C1=CC=C(C=C1F)NC1N=C2NC=C(C)C2=C(N=1)C1=CC(CC#N)=CC=C1
InChiKey: CGQCWMIAEPEHNQ-UHFFFAOYSA-N
Smiles: COC1=CC2=C(O)C3COC(=O)C=3C(=C2C=C1OC)C1C=C2OCOC2=CC=1
InChiKey: FZNPYIAZMDBRLC-RKNDTPCJSA-N
BACE1-IN-4 Size:Contact [email protected] for quotation the receptor complex is internalizedBACE1 IN 4 is a potent and highly selective BACE1 inhibitor, with an IC50 of 3. 8 nM and a Ki of 1. 9 nM, more selective at BACE1 over BACE2. Anti Alzheimers disease. Product information CAS Number: 2361157 92 6 Molecular Weight: 511. 57 Formula: C21H23F2N5O4S2 Chemical Name: N {3 [(5R) 3 amino 5 methyl 9,9 dioxo 2,9 dithia 4 azaspiro[5. 5]undec 3 en 5 yl] 4 fluorophenyl} 5 (fluoromethoxy)pyrazine 2 carboxamide Smiles: