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4R)-1-[(2S)-2-(14-amino-3
3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-[(pyridin-3-yl)methyl]piperazine-2-carboxamide
5-lactone is neutral
Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions
prolongs survial
Bcl-2/Bcl-xl inhibitor 1 16725 4R)-1-[(2S)-2-(14-amino-3Bcl 2 Bcl xl inhibitor 1 (compound 6) is a dual Bcl 2 and Bcl xl inhibitor with anti tumor activity, extracted from patent WO2018027097A1. Bcl 2 Bcl xl inhibitor 1 exhibits IC50 values of 2 nM and 5. 9 nM for Bcl 2 and Bcl xl, respectively. Product information CAS Number: 2180923 05 9 Molecular Weight: 882. 42 Formula: C45H48ClN7O8S Chemical Name: 4 (4 {[6 (4 chlorophenyl)spiro[3. 5]non 6 en 7 yl]methyl}piperazin 1 yl) N [4 ({[(2S) 1,4 dioxan 2
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